Given the relatively small size of the data on MS cards (64-256meg typically, few use the 512 and 1g MS) there is little reason to do a true "backup" function that produces some propietary compressed archive. A simple copy of the contents of the MS works extremely well and its a no brainer to find a single file in the copy to put back on the stick when you need to "restore".
Use Missing Sync to get a Mac desktop client for your Clie's "Data Import" applet. This will mount the MS on the desktop as a standard mounted volume. You can then simply copy all of the cards contents into a folder on your desktop machine. If you must have a compressed archive for some reason, you can easily use Stuffit to compress the copied folder once its on your Mac's HD.
Alternately, you can get a MS card reader (preferably an MS Pro compatible reader) and use it for reading the MS from your Mac. If you are successfully syncing with your Mac without Missing Sync, the card reader may well prove the less expensive alternative and if you get one that uses a USBmini5 connector, like some from Inland and Lexar, you net a second HotSync cable in the bargin. The current version of Missing Sync doesn't support the UX's "Int.Mem" partition so there is no read advantage to it over a separate card reader (except for klutzes like me who dropped and dented their T415 so that it won't release the card anymore...).
To "backup" my Int.Mem partition, I copy it to a "Backup" folder on my MS using the UX's built-in file manager and then copy the whole MS to my desktop.